DR. SANJAY KUMAR BHADADA
MBBS, MD (GENERAL MEDICINE), DM ENDOCRINOLOGY
DEPARTMENT OF ENDOCRINOLOGY
ROOM NO - 2, 4TH FLOOR BLOCK -F, NEHRU HOSPITAL
POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION & RESEARCH (PGIMER), CHNADIGARH
Dr. Sanjay Kumar Bhadada (MD, DM (Endocrinology and Metabolism), FICP, FRCPI and MNAMS) is working as an Additional Professor in the department of Endocrinology, PGIMER, Chandigarh, premier medical institute of country, known for its research and patient care worldwide . He is the founder and current secretary of Punjab and Chandigarh chapter of RSSDI. He is an Ex National Executive and current Secretary of Indian Society for Bone and Mineral Research (ISBMR). He is the regular speaker at annual conferences of RSSDI, Endocrine society of India (ESI) and ISBMR. He has more than 160 publications in high impact factor journals, speaks about his research aptitude. He has received prestigious awards like M N Sen Oration award by ICMR in 2013, PN Shah Oration award by Endocrine Society of India in 2010 & Prof. Survir Singh Visiting Professorship by Association of Physicians of India in 2011. He also delivered Sanofi Aventis senior lecturership at APICON and recently nominated for prestigious Prof. Shuvir singh oration award. He has research collaboration with International institutes like Henry Ford Hospital, Detroit, USA & Antwerep University, Belzium and national institutes like IIT Ropar, CDRI Lucknow, AIIMS New Delhi, Panjab University & IMTECH, Chandigarh. He is the Section Editor of the ESI manual of Endocrinology. His major field of interests is diabetes in young and bone and diabetes. He is core team member of simultaneous pancreas and kidney transplant program at PGIMER, Chandigarh. He was the organizing secretary of one of the best organized ESICON (year 2014) at PGIMER, Chandigarh.
His work on primary hyperparathyroidism (PHPT) is recognized throughout country. He made the first online Indian PHPT registry program (www.indianphptregistry.com) to compile the data on PHPT throughout Indiato better understand the epidemiology, clinical and biochemical aspects in PHPT from India and has published many papers on the different clinical and biochemical complications associated with PHPT.
He is also actively involved ineducating type 1 diabetes children and providing complementary insulin and glucostrips to poor and underprivileged young individuals with diabetes through social support groupcalled ADITI (Association of Diabetes (young) in Tricity ). He is founder and current secretary of ADITI.
- Primary Hyperparathyroidism
- Rare Metabolic Bone disorders
- Diabetes in Young
- Life member of European Calcified Tissue Society (ECTS)
- Life member of Association of physicians of India (API)
- Life member of Endocrine Society of India (ESI)
- Life member of Research Society for the Studies of Diabetes in India (RSSDI)
- Life member of Indian Society Bone and Mineral Research (ISBMR)
- Life member of Indian Menopausal Society
- Life member of Indian Thyroid Society (ITS) (Registration No. 1138)
- Indian Society for Pediatric and Adolescent Endocrinology (ISPAE).
- Indian Medical Association (IMA)
- Executive Secretary of Endocrine Society of India 2008-09
- Joint Secretary of Endocrine Society of India 2010-13
- Member of National Academy of Medical Sciences (MNAMS).
- Fellow of Indian College of Physicians (FICP).
- Founder governing council Member and Joint Secretory of World Non-communicable disease federation
- Young Investigator Award for year 2005 from Indian Society of Bone and Mineral Research.
- ISG-Systopic Award in 2009 from Indian Society of Gastroenterology for presenting paper on “Prevalence and Predictors of Abnormal Bone Metabolism in Adult Celiac Patients”
- P N Shah Memorial Oration award at Endocrine society of India conference (ESICON) in year 2010 at CMC, Vellore.
- SANOFI AVENTIS SENIOR Lectureship in diabetes at APICON, 2012, Kolkata.
- AR Seth Award for the year 2012 for the second best oral presentation at ESICON 2012 kolkata.
- Prof. Survir Singh Visiting Professorship by Association of Physicians India for year 2013
- ICMR M N SEN Oration award for year 2012on his research work on “Primary hyperparathyroidism (PHPT) in India”.
- To study gene expression for Vitamin D Receptor (VDR) and Calcium Sensing Receptor (CaSR) in patients with Primary Hyperparathyroidism (PHPT) and its correlation with clinical outcome (Funded by- Indian Council of Medical Research (ICMR), India , Oct 2010 – Sept 2013)
- Identification of differentially expressed proteins in parathyroid tumors and their clinical correlation with the disease (Funded by - Indian Council of Medical Research (ICMR), India , Oct 2012 – Sept 2015)
- To study promoter methylation status of CDKN2A, CDKN2B and RASSF1A gene in primary hyperparathyroidism (Funded by – Intramural grant from PGIMER, April 2013 – March 2015)
- Expression profiling of mitogen activated protein Kinase (MAPK) signaling pathway molecules in patients with sporadic primary hyperparathyroidism and correlation with disease indices (Funded by - Endocrine Society of India, April 2016 – March 2018)
- Functional and genetic characterization of microRNAs involved in sporadic parathyroid adenomas (Funded by - Intramural research grant by PGIMER, April 2015 – March 2017)
- To study the promoter methylation of transcriptional regulators of calcium sensing receptor (CASR) in sporadic parathyroid tumors (Funded by - Intramural research grant by PGIMER, April 2016 – March 2018)
PUBLICATIONS (Journal Articles - Only on PHPT)
- Giant Cell Lesions Associated with Primary Hyperparathyroidism. Rai S, Rattan V, Bhadada SK. J Maxillofac Oral Surg. 2015;14(4):930-4.
- The resolution of anemia after curative parathyroidectomy is sustained even after a decade.Bhadada SK, Arya AK, Parthan G, Singh P. Indian J Endocrinol Metab. 2015 ;19 (5):691-2.
- Changes in clinical & biochemical presentations of primary hyperparathyroidism in India over a period of 20 years.Shah VN, Bhadada S, Bhansali A, Behera A, Mittal BR. Indian J Med Res. 2014 ;139(5):694-9
- Changes in parathyroid proteome in patients with primary hyperparathyroidism due to sporadic parathyroid adenomas.Varshney S, Bhadada SK, Arya AK, Sharma S, Behera A, Bhansali A, Rao SD. Clin Endocrinol (Oxf). 2014 Oct;81(4):614-20.
- Effect of gender, biochemical parameters & parathyroid surgery on gastrointestinal manifestations of symptomatic primary hyperparathyroidism.Shah VN, Bhadada SK, Bhansali A, Behera A, Bhattacharya A, Nahar U, Bhasin D, Vadera B. Indian J Med Res. 2014 Feb;139(2):279-84.
- Effect of 25 (OH) D replacements in patients with primary hyperparathyroidism (PHPT) and coexistent vitamin D deficiency on serum 25(OH) D, calcium and PTH levels: a meta-analysis and review of literature.Shah VN, Shah CS, Bhadada SK, Rao DS. Clin Endocrinol (Oxf). 2014 ;80(6):797-803.
- Pseudoarthrosis and fracture: interaction between severe vitamin D deficiency and primary hyperparathyroidism. Rastogi A, Bhadada SK, Bhansali A. Singapore Med J. 2013 Nov;54(11):e224-7.
- Methylation status of the CpG islands in vitamin D and calcium-sensing receptor gene promoters does not explain the reduced gene expressions in parathyroid adenomas.Varshney S, Bhadada SK, Sachdeva N, Arya AK, Saikia UN, Behera A, Rao SD. J Clin Endocrinol Metab. 2013 ;98(10):E1631-5.
- Simultaneous expression analysis of vitamin D receptor, calcium-sensing receptor, cyclin D1, and PTH in symptomatic primary hyperparathyroidism in Asian Indians.Varshney S, Bhadada SK, Saikia UN, Sachdeva N, Behera A, Arya AK, Sharma S, Bhansali A, Mithal A, Rao SD. Eur J Endocrinol. 2013, 7;169(1):109-16.
- Unusual association of primary hyperparathyroidism, papillary thyroid carcinoma, and follicular adenoma in a young female. Sridhar S, Saikia UN, Bhadada SK, Bhansali A, Singh R, Behra A. Indian J Endocrinol Metab. 2013;17(2):355-6.
- Oro-mandibular manifestations of primary hyperparathyroidism.Rai S, Bhadada SK, Rattan V, Bhansali A, Rao DS, Shah V.Indian J Dent Res. 2012; 23(3):384-7.
- Chief cell and clear cell parathyroid adenoma do not influence clinical and biochemical expression of the sporadic primary hyperparathyroidism. Varshney S, Bhadada SK, Nahar U, Shah VN, Bhansali A, Behera A. Endocrine. 2013;43(2):440-3.
- Influence of age and gender on presentation of symptomatic primary hyperparathyroidism.Shah VN, Bhadada SK, Bhansali A, Behera A, Mittal BR, Bhavin V.J Postgrad Med. 2012;58(2):107-11.
- Anemia and thrombocytopenia improves after curative parathyroidectomy in a patient of primary hyperparathyroidism (PHPT).Bhadada SK, Sridhar S, Ahluwalia J, Bhansali A, Malhotra P, Behera A, Mittal BR. J Clin Endocrinol Metab. 2012; 97(5):1420-2.
- Pulmonary function tests in patients with primary hyperparathyroidism.Bhadada SK, Agrawal A, Shah VN, Bhansali A, Behera A, Bhattacharya A, Nahar U. Indian J Endocrinol Metab. 2012;16(3):414-6.
- Changes in serum leptin and adiponectin concentrations and insulin resistance after curative parathyroidectomy in moderate to severe primary hyperparathyroidism.Bhadada SK, Bhansali A, Shah VN, Rao DS. Singapore Med J. 2011;52(12):890-3
- Spectrum of single photon emission computed tomography/computed tomography findings in patients with parathyroid adenomas.Chakraborty D, Mittal BR, Harisankar CN, Bhattacharya A, Bhadada S. Indian J Nucl Med. 2011;26(1):52-5.
- High prevalence of cholelithiasis in primary hyperparathyroidism: a retrospective analysis of 120 cases.Bhadada SK, Bhansali A, Shah VN, Behera A, Ravikiran M, Santosh R. Indian J Gastroenterol. 2011;30(2):100-1.
- A pilot study on hypothalamo-pituitary-adrenocortical axis in primary hyperparathyroidism.Rajput R, Bhansali A, Bhadada SK, Behera A, Mittal BR, Sialy R, Khandelwal N. Indian J Med Res. 2009;130(4):418-22.
- Characteristics of primary hyperparathyroidism in adolescents.Bhadada SK, Bhansali A, Dutta P, Behera A, Chanukya GV, Mittal BR. J Pediatr Endocrinol Metab. 2008;21(12):1147-53
- Worsening of bone disease after curative surgery in primary hyperparathyroidism. Bhansali A, Shanmugasundar G, Bhadada SK, Walia R, Ravikumar P BMJ Case Rep. 2009;.pii: bcr12.2008.1357.
- Anaemia and marrow fibrosis in patients with primary hyperparathyroidism before and after curative parathyroidectomy.Bhadada SK, Bhansali A, Ahluwalia J, Chanukya GV, Behera A, Dutta P. Clin Endocrinol (Oxf). 2009;70(4):527-32.
- Very low or undetectable intact parathyroid hormone levels in patients with surgically verified parathyroid adenomas.Bhadada SK, Cardenas M, Bhansali A, Mittal BR, Behera A, Chanukya GV, Nahar U, Rao DS. Clin Endocrinol (Oxf). 2008 ;69(3):382-5.
- Ultrasonography in detection of single and multiple abnormal parathyroid glands in primary hyperparathyroidism: comparison with radionuclide scintigraphy and surgery.Bhansali A, Masoodi SR, Bhadada S, Mittal BR, Behra A, Singh P. Clin Endocrinol (Oxf). 2006;65(3):340-5.
- Giant mediastinal parathyroid adenoma presenting as bilateral brown tumour of mandible: a rare presentation of primary hyperparathyroidism. Talukder S, Behera A, Bhadada S, Mitra S. BMJ Case Rep. 2017;2017.
- Comparative Effectiveness of Ultrasonography, 99mTc-Sestamibi, and 18F-Fluorocholine PET/CT in Detecting Parathyroid Adenomas in Patients With Primary Hyperparathyroidism. Thanseer N, Bhadada S, Sood A, Mittal BR, Behera A, Gorla AKR, Kalathoorakathu RR, Singh P, Dahiya D, Saikia UN, Rao SD. Clin Nucl Med. 2017. doi: 10.1097/RLU.0000000000001845
- Prevalence and predictors of primary hyperparathyroidism among patients with urolithiasis. Sharma S, Rastogi A Bhadada S, Singh P, Varshney S, Behera A, Bhansali A, Singh SK, Rao DS. Endocr Pract. 2017. doi: 10.4158/EP171759.OR
- Sensitive Detection of a Small Parathyroid Adenoma Using Fluorocholine PET/CT: A Case Report. Padinhare-Keloth TNTK Bhadada S, Sood A, Kumar R, Behera A, Radotra BD, Mittal BR. Nucl Med Mol Imaging. 2017;51(2):186-189.
- Promoter hypermethylation inactivates CDKN2A, CDKN2B and RASSF1A genes in sporadic parathyroid adenomas. Arya AK, Bhadada S, Singh P, Sachdeva N, Saikia UN, Dahiya D, Behera A, Bhansali A, Rao SD. Sci Rep. 2017;7(1):3123.
- Sensitive Detection of a Small Parathyroid Adenoma Using Fluorocholine PET/CT: A Case Report. Padinhare-Keloth TNTK, Bhadada S, Arya AK, Mukhopadhyay S, Khadgawat R, Sukumar S, Lodha S, Singh DN, Sathya A, Singh P, Bhansali A. J Bone Miner Metab. 2017. doi: 10.1007/s00774-017-0833-8.
- Primary hyperparathyroidism: insights from the Indian PHPT registry Bhadada S, Sood A, Kumar R, Behera A, Radotra BD, Mittal BR. Nucl Med Mol Imaging. 2017;51(2):186-189.
- Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus. Khan AA, Hanley DA, Rizzoli R, Bollerslev J, Young JE, Rejnmark L, Thakker R, D'Amour P, Paul T, Van Uum S, Shrayyef MZ, Goltzman D, Kaiser S, Cusano NE, Bouillon R, Mosekilde L, Kung AW, Rao SD Bhadada S, Clarke BL, Liu J, Duh Q, Lewiecki EM, Bandeira F, Eastell R, Marcocci C, Silverberg SJ, Udelsman R, Davison KS, Potts JT Jr, Brandi ML, Bilezikian JP. Osteoporos Int. 2017 ;28(1):1-19.
- Effect of curative parathyroidectomy on insulin resistance. Putnam R, Dhibar DP, Varshney S, Behera A, Mittal BR, Bhansali A, Rao SD, Bhadada S, . Indian J Endocrinol Metab. 2016 ;20(6):784-789.
- Sudhaker d. Rao, Sanjay Kr Bhadada and A. Michael Parfitt. Parathyroid Growth: Normal and Abnormal in book “The Parathyroids”, Third Edition, Editors John P. Bilezikian, Robert Marcus, Micheal A. Levine, Claudio Marcocci, Shonni J Silverbeg, John T. Potts Jr. Elsevier, 2014. p255-272
- Sudhakar D Rao, Bhadada SK, Role of Vitamin D Nutrition in Metabolic Syndrome and Cardiovascular Risk Published by ICP monograph 2013.
- Bhadada SK, D Sudhakar Rao. Osteoporosis: Nonpharmacological management of osteoporosis Published by nature publishing group; 2012,p39-48.
- Bhadada SK, Mithal A. A Primary Hyperparathyroidism: An Indian Perspective (eds.) ESI Manual of Clinical Endocrinology. Published by Endocrine society of India; 2012,p503-510.
- Bhadada S, Bhansali A, Bhat RV. Clinical presentation of primary hyperparathyroidism. An Asian Perspective on Nutritional and Metabolic Bone and stone Disease. CBS publisher & Distributor, New Delhi; 2008, p-480-487.
- Bhat RV, Bhadada S. Familial hypocalciuric hypercalcimia. An Asian Perspective on Nutritional and Metabolic Bone and stone Disease. CBS publisher & Distributor, New Delhi,2008: p509-513.
- Shriram M, Bhadada S. Phosphate Homeostasis. An Asian Perspective on Nutritional and Metabolic Bone and stone Disease. . CBS publisher & Distributor, New Delhi,2008.p133-139.
PHPT WORKING GROUP IN PGIMER, CHANDIGARH
We work closely with a number of scientists in India and abroad
Dr. Rajesh Kahadgawat, Additional Professor, AIIMS New Delhi
Dr.Ritu Trivedi, Sr. Scientist, CDRI Lucknow,
Dr.Navin Kumar, Assistant Professor IIT Ropar
Dr Sudhaker D Rao, Henry Ford Hospital Detroit USA
Dr. Wim Van Hul- Antwerp, Belgium